Weakly supervised segmentation of COVID-19 infection with local lesion coherence on CT imagesResearch article Published on 2023-01-012022-10-05 Journal: Biomedical Signal Processing and Control [Category] 진단, 치료기술, [키워드] absence Accuracy Algorithm approach Attention automated chain Characteristics Clinical diagnosis Complete complex Computed tomography COVID-19 COVID-19 infection CT scan dataset deep learning diagnostic edge effective expression gold standard help IMPROVE individual information labeling labor-intensive lesion Local Local Coherence Lung infection module Novel coronavirus offer overcome public health reaction Region RT-PCR scale seeking Segmentation severity the disease time-consuming Weakly Supervised [DOI] 10.1016/j.bspc.2022.104099 [Article Type] Research article
A nasal omicron vaccine booster elicits potent neutralizing antibody response against emerging SARS-CoV-2 variants비강 오미크론 백신 부스터는 새로운 SARS-CoV-2 변이체에 대한 강력한 중화 항체 반응을 이끌어냅니다.Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] absence adjuvants administration antibody Antibody Response boost booster Bronchoalveolar lavage caused clinical trial composed COVID-19 COVID-19 pandemic current deaths delta variant described disease severity domain dose effective Elevation elicit evidenced FIVE fused human infection human infections humans IgA Immunity immunogen intranasal leads mice MOST mucosal nasal nasal protein vaccine booster Neutralizing activity neutralizing antibody Neutralizing antibody response omicron Omicron variant omicron variant. Protein Receptor binding domain reduce respiratory SARS-CoV-2 SARS-CoV-2 nucleoprotein SARS-CoV-2 spike SARS-CoV-2 transmission SARS-CoV-2 variant severity significantly single dose suggested the antibody response the disease vaccination Vaccine virus infection wild-type [DOI] 10.1080/22221751.2022.2053365 PMC 바로가기 [Article Type] Article
Clinical features and high-resolution chest computerized tomography findings of children infected by the B.1.617.2 variant of coronavirus disease 2019Article Published on 2022-12-012022-11-16 Journal: Annals of Medicine [Category] COVID19(2023년), SARS, 변종, [키워드] absence age analysed analyses B.1.617.2 B.1.617.2 (Delta) variant biochemical Blood Cell Chest Chest CT chest. children China clinical clinical symptom Clinical symptoms collected Computerized tomography Concentration consolidation coronavirus disease corpuscular correlated correlation cough COVID-19 CT CT finding Delta Diagnosis Disease diagnosis disease stage distribution elevated Factor feature Fever Follow-up ground-glass opacity group Haemoglobin High-resolution imaging Infection Laboratory Laboratory tests lymphocyte males Mild monocyte Nanjing no difference pathological change Patient percentage pharyngeal Platelet regression analysis serum alkaline phosphatase significant effect Stage stages statistically significant Subtypes Symptom Symptoms the disease variant Volume [DOI] 10.1080/07853890.2022.2114608 PMC 바로가기
Assessing the transition of COVID-19 burden towards the young population while vaccines are rolled out in China중국에서 백신이 출시되는 동안 젊은 인구에 대한 COVID-19 부담의 전환 평가Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, [키워드] absence Admissions age Assessing cause children China Chinese coronavirus disease Coronavirus disease 2019 Coverage COVID-19 deaths decrease Delta delta variant disease Effectiveness effort eligible Epidemics fatality groups highlight Hospitalization hospitalizations incidence include individual Infants Infection intensive care lineages novel Novel coronavirus novel coronavirus disease Novel coronavirus disease 2019 Older age over SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 transmission symptomatic infection symptomatic infections target population transition transition of disease burden Transmission triggered vaccinated against COVID-19 vaccination vaccination. Vaccine widespread [DOI] 10.1080/22221751.2022.2063073 PMC 바로가기 [Article Type] Article
Effects of the Omicron variant on perinatal outcomes in full-term neonatesArticle Published on 2022-11-032022-11-16 Journal: BMC Pediatrics [Category] SARS, 변종, [키워드] absence analyzed APGAR score complications conducted coronavirus disease COVID COVID-19 criteria demonstrated Effect enrolled exclusion criteria Full-term neonate Infection investigated Isolation Korean Mortality mother Neonatal resuscitation Neonate Newborn non-infectious omicron Omicron variant outcome outcomes Perinatal Perinatal outcomes. Pregnancy required Research Respiratory Support Self-isolation Seven significant difference single center symptomatic symptomatic and asymptomatic tachypnea variant were excluded [DOI] 10.1186/s12887-022-03690-8 PMC 바로가기
Clinical onset of CNS demyelinating disease after COVID-19 vaccination: denovo disease?Article Published on 2022-11-012022-11-15 Journal: Multiple sclerosis and related disorders [Category] SARS, 진단, [키워드] absence age association case sery cell counts cerebrospinal fluid Characteristics clinical Clinical characteristics CNS Cohort comparable COVID-19 CSF demyelinating Demyelinating disease disease Evidence Follow-up glycoprotein indicate initial lesion magnetic resonance imaging MRI Multiple multiple sclerosis Multiple sclerosis (MS) Myelin Myelin oligodendrocyte glycoprotein antibody-related disease (MOGAD) Neuroinflammation occurred Optical coherence tomography parameter Patient reported SARS-CoV-2 SARS-CoV-2- (COVID-19) vaccination. sclerosis vaccination [DOI] 10.1016/j.msard.2022.104175 PMC 바로가기
Highly sensitive aptasensor for the detection of SARS-CoV-2-RBD using aptamer-gated methylene blue@mesoporous silica film/laser engraved graphene electrodeArticle Published on 2022-11-012022-11-15 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, [키워드] absence acute respiratory syndrome Analysis aptamer Aptamer gated-mesoporous silica film aptasensor C-reactive protein Coronavirus-2 Coverage detect Electrochemical measurement electrostatic encapsulation group high affinity indicated influenza A virus limit of detection phosphate porous probe Saliva SARS-CoV-2-RBD SARS-CoV-2-RBD. the receptor-binding domain was recorded [DOI] 10.1016/j.bios.2022.114556 PMC 바로가기
Pandemic driven innovation: A pilot evaluation of an alternative respiratory pathogen collection deviceArticle Published on 2022-11-012022-11-16 Journal: The American journal of emergency medicine [Category] SARS, 유전자 메커니즘, [키워드] absence All participant amplification communicable disease COVID-19 demonstrated determine diagnostic enrolled evaluated faster favor feedback fused gold standard identify inhibitor Innovation Interpretation invasive mechanism nasopharyngeal Nasopharyngeal swab nucleic acids participant Patient PCR PCR cycle PCR testing pilot study polymerase chain positive producing real-time reverse transcriptase receiving respiratory respiratory pathogen respiratory virus Result resulting RNase P RNAseP RT-qPCR Self-collection respiratory pathogen device. specimen study participant TaqPath tested threshold [DOI] 10.1016/j.ajem.2022.08.047 PMC 바로가기
Serum neurofilament light chain levels in Covid-19 patients without major neurological manifestationsArticle Published on 2022-11-012022-11-15 Journal: Journal of Neurology [Category] COVID19(2023년), SARS, 바이오마커, [키워드] absence Admission baseline Biomarker Blood Brescia C-reactive protein change controls correlated COVID-19 CRP D-dimer disease severity evaluated Evidence excluded explained fibrinogen healthy controls Hospital stay Hospitalized hypoxic Increased longitudinal measure Neuroaxonal damage neurofilament Neurofilament light chain (NFL) neurological manifestation neurological manifestations neurotoxic PaO2/FiO2 ratio parameters Patient patients plasma promote reported respiratory respiratory impairment SARS-CoV-2 scale serum serum creatinine serum CRP Serum level serum sample serum. significantly Simoa systemic inflammation Variation were measured White blood cell with mild disease [DOI] 10.1007/s00415-022-11233-5 PMC 바로가기
Concordance of B- and T-cell responses to SARS-CoV-2 infection, irrespective of symptoms suggestive of COVID-19Article Published on 2022-11-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 진단, [키워드] absence Analysis anti-IgG antibodies antibody Antibody titer Cellular immune response cellular immunity Cohort correlated correlated strongly COVID COVID-19 COVID-19 pandemic ELISA Evidence Final First wave IgG individual pandemic participant positive antibody response Regulatory response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 peptide SARS-CoV2 infection spike Symptom symptom response. symptomatic and asymptomatic T cell T-cell T-cell Response TwinsUK were assessed [DOI] 10.1002/jmv.28016 PMC 바로가기